Longevity Master Stack
LONGEVITYQuick Specifications
| Vial Size | SOLD AS 4-PART LONGEVITY PROTOCOL |
|---|---|
| BAC Water | SEE INDIVIDUAL PEPTIDE ENTRIES |
| Amount Per Unit | SEE INDIVIDUAL ENTRIES |
| Recommended Dose | SEE INDIVIDUAL PEPTIDE ENTRIES FOR PRECISE DOSING |
| Frequency | EPITHALON DAILY 10 DAYS; THYMALIN DAILY 10 DAYS; MOTS-C 3X PER WEEK; SS-31 DAILY |
| Injection Type | SUBCUTANEOUS (ALL FOUR COMPONENTS) |
| Timing | Phase 1 (Days 1-10): Epithalon + Thymalin together daily (Khavinsky dual bioregulator protocol — these two are always run simultaneously). Phase 2 (Weeks 3-10): Add MOTS-c every 5 days SubQ. SS-31: daily SubQ 100-300mcg throughout all phases. Complete 2 full cycles per year. See individual entries for precise reconstitution and dosing of each component. |
Research Overview
The Longevity Master Stack is the most comprehensive anti-aging research protocol available on this site — four peptides targeting four distinct biological aging mechanisms simultaneously, with no mechanistic overlap between any of the four components. Epithalon (tetrapeptide bioregulator, Khavinsky lab) targets the pineal-telomere axis: it stimulates telomerase activity to lengthen critically short telomeres in aging cells, restores declining melatonin secretion from the involuting pineal gland, and regulates the broader neuroendocrine aging axis. Thymalin (thymic bioregulator, Khavinsky lab) addresses immune aging — the progressive atrophy of thymic function that drives T-cell exhaustion and immunosenescence from early adulthood. In Khavinsky's landmark 6-year longitudinal study, elderly patients receiving combined Epithalon and Thymalin treatment showed significantly reduced mortality compared to controls. MOTS-c (mitochondrial-derived peptide, USC) drives metabolic reprogramming via AMPK activation, restoring mitochondrial biogenesis and metabolic flexibility that decline with age. SS-31 (elamipretide, approved September 2025 as Forzinity for Barth syndrome) repairs the inner mitochondrial membrane by stabilizing cardiolipin — the phospholipid that anchors the electron transport chain — reversing the structural degradation that reduces energy output in aging mitochondria. Each of the four compounds operates through a completely independent mechanism (epigenetic/telomere, immune, mitochondrial biogenesis, mitochondrial membrane) — they work additively rather than redundantly, maximizing the research protocol's coverage of the biology of aging. For research and educational purposes only.
Commonly Studied With
These peptides are frequently researched alongside Longevity Master Stack: Epithalon (10mg) / Thymalin (10mg) / MOTS-c (5mg) / SS-31 (7mg) due to complementary mechanisms:
For research-grade the Longevity Master Stack with third-party Certificate of Analysis documentation, Peptide Hub recommends Apollo Peptide Sciences. Apollo Peptide Sciences carries all four components of the Longevity Master Stack. Affiliate disclosure: we may earn a commission on purchases through this link.
Longevity Master Stack: Epithalon (10mg) / Thymalin (10mg) / MOTS-c (5mg) / SS-31 (7mg) information on this page is for research and educational purposes only. This content is not FDA-approved, does not constitute medical advice, and should not be used to guide personal health decisions. Consult a qualified healthcare professional before using any research compound.
Dose Calculator
Enter your target dose to calculate the volume to draw.
Recommended dose: SEE INDIVIDUAL PEPTIDE ENTRIES FOR PRECISE DOSING