Triptorelin
REPRODUCTIVE HEALTHQuick Specifications
| Vial Size | 2MG |
|---|---|
| BAC Water | 2ML |
| Amount Per Unit | 0.01MG PER UNIT |
| Recommended Dose | 0.1MG (10 UNITS) — SINGLE DOSE FOR HPG RESTART |
| Frequency | SINGLE DOSE PROTOCOL — NOT FOR REPEATED USE |
| Injection Type | SUBCUTANEOUS |
| Timing | Single 0.1mg (10 unit) dose for HPG axis restart. Administer 4-6 weeks after last exogenous androgen dose. Monitor LH, FSH, total testosterone at 2 and 4 weeks post-administration. Not for chronic or repeated dosing — sustained agonism causes receptor downregulation and hormonal suppression rather than stimulation. The full 2mg vial provides 20 single restart doses — store remaining reconstituted solution at 4C and use within 30 days. |
Research Overview
Triptorelin is a long-acting synthetic GnRH (gonadotropin-releasing hormone) agonist decapeptide with approximately 100 times the receptor binding potency of native GnRH. Triptorelin's primary research application in the peptide community is HPG (hypothalamic-pituitary-gonadal) axis restart after suppression from exogenous testosterone (TRT) or anabolic androgen use — a protocol where a single low dose (0.1mg) triggers a powerful initial LH and FSH flare response by massively stimulating pituitary GnRH receptors before the agonist-induced downregulation of those receptors occurs. This flare effect is exploited in restart protocols because an HPG-suppressed axis responds to the initial GnRH surge with a compensatory LH spike that stimulates Leydig cell testosterone production. In sustained use (as in prostate cancer treatment), continuous GnRH agonism causes receptor downregulation and hormonal castration — the opposite of the restart effect. The restart protocol is a precise single-dose application. Approved medically as Trelstar (USA) and Decapeptyl (EU) for prostate cancer, endometriosis, and precocious puberty in long-acting depot formulations. The restart application uses a very small single subcutaneous dose, not a depot preparation. Post-TRT restart: wait 4-6 weeks after last testosterone dose before administration. Monitor LH, FSH, and total testosterone at 2 and 4 weeks post-dose to confirm axis recovery. For research and educational purposes only. Consult a qualified healthcare professional.
For research-grade Triptorelin with third-party Certificate of Analysis documentation, Peptide Hub recommends Apollo Peptide Sciences. Apollo Peptide Sciences carries Triptorelin with verified COA documentation. Affiliate disclosure: we may earn a commission on purchases through this link.
Triptorelin: 2mg information on this page is for research and educational purposes only. This content is not FDA-approved, does not constitute medical advice, and should not be used to guide personal health decisions. Consult a qualified healthcare professional before using any research compound.
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Recommended dose: 0.1MG (10 UNITS) — SINGLE DOSE FOR HPG RESTART