Quick Specifications

Vial Size 5MG
BAC Water 1ML
Amount Per Unit 0.05MG PER UNIT
Recommended Dose 500MCG (10 UNITS)
Frequency AS NEEDED (2 HOURS BEFORE SEXUAL ACTIVITY)
Injection Type SUBCUTANEOUS
Timing Not To Exceed 20 Units (Consult With Doctor)

Research Overview

SIGNALS CENTRAL NERVOUS SYSTEM TO ENHANCE BLOOD FLOW, AROUSAL AND LIBIDO IN MEN AND WOMEN

How It Works

Melanocortin Receptor Agonism

PT-141 (bremelanotide) is a synthetic analogue of alpha-melanocyte-stimulating hormone (alpha-MSH) that acts as an agonist at melanocortin receptors MC3R and MC4R. These receptors are expressed in the hypothalamus and limbic system — brain areas governing sexual response and arousal.

Central Nervous System Mechanism

Unlike phosphodiesterase inhibitors (e.g., sildenafil) which act peripherally on blood vessels, PT-141 works centrally through the nervous system. It activates the hypothalamic melanocortin pathway to directly influence sexual motivation and arousal — a fundamentally different mechanism.

FDA-Approved Foundation

Bremelanotide (PT-141) received FDA approval as Vyleesi in 2019 for hypoactive sexual desire disorder (HSDD) in premenopausal women, validating its central melanocortin mechanism. Research continues to explore applications in male sexual dysfunction.

Research & Educational Purposes Only

PT-141: 5mg information on this page is for research and educational purposes only. This content is not FDA-approved, does not constitute medical advice, and should not be used to guide personal health decisions. Consult a qualified healthcare professional before using any research compound.

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in mcg

Recommended dose: 500MCG (10 UNITS)