VIP (Vasoactive Intestinal Peptide): 10mg
Anti inflammatoryDescription
Vip (vasoactive intestinal peptide) is a 28-amino acid neuropeptide and potent endogenous immune modulator found in the brain, gut, and throughout the nervous system. vip binds to vpac1 and vpac2 receptors on immune cells, reducing production of pro-inflammatory cytokines including il-6 and tnf-alpha by up to 40% in controlled research settings, without broadly suppressing the immune system — a critical distinction from corticosteroids. this selectivity makes it relevant in research for mast cell activation syndrome (mcas), chronic inflammatory response syndrome (cirs/mold illness), inflammatory bowel disease, pulmonary hypertension, copd, and rheumatoid arthritis. vip also synchronizes the suprachiasmatic nucleus (the brain's master clock) with light-dark cycles, making it relevant in circadian rhythm and sleep disorder research. administration note: vip has a plasma half-life of only 2-3 minutes when administered systemically. intranasal delivery routes bypass this issue by achieving direct cns transport via olfactory nerve at concentrations 10-15x higher than subcutaneous dosing. titration should be gradual — start low and increase over 2-3 weeks. vasodilatory flushing is common during initial administration and typically resolves as the body adapts. for research and educational purposes only. consult a qualified healthcare professional.
Specifications
| Amount in Vial | 10mg |
|---|---|
| BAC Water | 2ml |
| Amount per Unit | 0.05mg per unit |
| Recommended Dose | 50mcg to 200mcg (1 to 4 units) |
| Frequency | Daily or twice daily |
| Injection Type | Subcutaneous or intranasal |
| Timing | Titrate up gradually from 50mcg. Intranasal preferred for CNS and circadian applications. SubQ for systemic anti-inflammatory use. Commonly used in MCAS stacks alongside LL-37, KPV, and TA-1. |
Dose Calculator
Based on 0.05mg per unit (100-unit insulin syringe)
Quick Reference
Reconstitution
Vial size: 10mg
Add BAC water: 2ml
Concentration: 0.05mg per unit
For research and educational use only.
This page provides research dosing information only. Not intended as medical advice. Consult a qualified professional before any use.