TB-500: 5mg

Description

Tb-500 is a synthetic 7-amino acid peptide corresponding to amino acids 17–23 of thymosin beta-4 (tβ4), a naturally occurring 43-amino acid protein found at high concentrations in blood platelets and wound fluid. its central mechanism is g-actin sequestration — by binding to monomeric actin, tb-500 regulates cytoskeletal organization and enables rapid cell migration essential for tissue repair. different segments of the molecule address distinct functions: amino acids 1–4 drive anti-inflammatory and anti-fibrotic effects; amino acids 1–15 contribute to anti-apoptotic properties; amino acids 17–23 handle actin binding, angiogenesis, and dermal wound repair. in preclinical wound models, tb-500 administration increased re-epithelialization by 42% at day 4 and 61% at day 7 compared to controls, with thicker collagen fiber formation and reduced scarring. research has also explored its cardioprotective effects following cardiac injury, spinal cord neuroprotection, and corneal wound healing. a 2024 study confirmed activation of the wnt/β-catenin pathway, a primary driver of cell proliferation and tissue homeostasis. tb-500 is frequently studied alongside bpc-157 due to their complementary mechanisms. for research and educational purposes only. not fda-approved.

Specifications

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