Single Regulator (SIA-31-C18): 2mg

Weight management

Description

Sia-31-c18 (single regulator) is a 31-amino acid glp-1 receptor agonist belonging to the peptide receptor modulator research series. it is a semaglutide-class single incretin agonist featuring a c18 fatty diacid (octadecanedioyl) side chain attached via a γ-glu-2x aeea linker at lys20, enabling albumin binding and extended half-life comparable to once-weekly dosing formats. the backbone closely mirrors the glp-1 incretin sequence with aib (alpha-aminoisobutyric acid) substitutions at key positions for dpp-4 resistance and enhanced receptor affinity. cas: 910463-68-2. structurally analogous in class to semaglutide. once-weekly subcutaneous injection. key reference literature: wilding et al. (nejm 2021) — once-weekly semaglutide in adults with overweight or obesity, 15% mean weight loss at 68 weeks; lincoff et al. (nejm 2023) — semaglutide and cardiovascular outcomes in obesity without diabetes; perkovic et al. (nejm 2024) — semaglutide effects on chronic kidney disease.

Specifications

Amount in Vial 2mg
BAC Water 1ml
Amount per Unit 0.02mg per unit
Recommended Dose titrate up from 250mcg to 2mg (12 to 100 units)
Frequency 1x per week
Injection Type Subcutaneous
Timing Same Day Every Week / Starting Dose Is 250 MCG — Titrate Slowly

Dose Calculator

Based on 0.02mg per unit (100-unit insulin syringe)

Quick Reference

Category Weight management
Dose Range titrate up from 250mcg to 2mg (12 to 100 units)
Frequency 1x per week
Route Subcutaneous

Reconstitution

Vial size: 2mg

Add BAC water: 1ml

Concentration: 0.02mg per unit

For research and educational use only.

This page provides research dosing information only. Not intended as medical advice. Consult a qualified professional before any use.

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