SHLP2 (Small Humanin-Like Peptide 2): 2mg
Mitochondrial functionDescription
Shlp2 (small humanin-like peptide 2) is a 20-amino acid mitochondria-encoded peptide discovered in 2016 by researchers at the usc davis school of gerontology, encoded within the 12s ribosomal rna region of the mitochondrial genome — the same genomic locus that encodes humanin. shlp2 belongs to the shlp family (shlp1-6), all sharing structural homology with humanin but exerting distinct biological profiles. shlp2's primary mechanisms include cytoprotection against oxidative stress-induced cell death (analogous to humanin's protective effect), regulation of anabolic hormone signaling — it modulates igf-1 responsiveness and improves insulin sensitivity in aging models — and mitochondrial quality maintenance. shlp2 levels decline measurably with age, paralleling humanin's age-related decline and suggesting a coordinated mitochondrial aging response. unlike mots-c (which activates ampk for metabolic reprogramming) and ss-31 (which repairs membrane structural integrity), shlp2 functions primarily in cellular protection and anabolic signaling preservation — a distinct fourth role in the mitochondrial-derived peptide family. shlp2 completes the mitochondrial research protocol alongside humanin (cytoprotection/anti-apoptosis), mots-c (metabolic reprogramming), and ss-31 (membrane repair). research on shlp2 is earlier-stage than humanin and mots-c but rapidly expanding. for research and educational purposes only.
Specifications
| Amount in Vial | 2mg |
|---|---|
| BAC Water | 2ml |
| Amount per Unit | 0.01mg per unit |
| Recommended Dose | 50mcg to 200mcg (5 to 20 units) |
| Frequency | Every other day or 3x per week |
| Injection Type | Subcutaneous |
| Timing | Morning SubQ injection. 8-12 week research cycles. Completes the mitochondrial-derived peptide family alongside Humanin, MOTS-c, and SS-31. Benefits are long-term and cellular — expect 4-8 weeks before effects are measurable. Store at -20C before reconstitution; use within 30 days. |
Dose Calculator
Based on 0.01mg per unit (100-unit insulin syringe)
Quick Reference
Reconstitution
Vial size: 2mg
Add BAC water: 2ml
Concentration: 0.01mg per unit
For research and educational use only.
This page provides research dosing information only. Not intended as medical advice. Consult a qualified professional before any use.