MOTS-c: 10mg

Mitochondrial function

Description

Mots-c (mitochondrial orf of the 12s rrna type-c) is a 16-amino acid peptide uniquely encoded within the mitochondrial genome — one of the few known peptides not originating from nuclear dna. this gives it a direct and fundamental relationship with mitochondrial metabolic state. under metabolic stress, mots-c translocates from mitochondria to the cell nucleus, where it binds stress-response transcription factors nrf2 and atf1 to reprogram cellular metabolism. its primary signaling mechanism activates ampk (amp-activated protein kinase) — the same master metabolic switch triggered by intense exercise — which drives glucose uptake, fatty acid oxidation, and mitochondrial biogenesis. in animal research: a 2021 nature communications study showed mots-c enhanced physical performance across age groups; a 2022 study showed a single dose improved running time by 12% and distance by 15%; a 2025 nature study demonstrated mots-c prevents pancreatic islet cell senescence, reducing diabetes progression. mots-c levels decline approximately 21% between ages 18–30 and ages 70–81. for research and educational purposes only.

Specifications

Amount in Vial 10mg
BAC Water 1ml
Amount per Unit 0.1mg per unit
Recommended Dose 5mg - 10mg (50 units - 100 units)
Frequency 1 injection every 5 days for 20 days
Injection Type Subcutaneous
Timing 3x Annually - If Type 2 Diabetic 1mg EOD

Dose Calculator

Based on 0.1mg per unit (100-unit insulin syringe)

Quick Reference

Category Mitochondrial function
Dose Range 5mg - 10mg (50 units - 100 units)
Frequency 1 injection every 5 days for 20 days
Route Subcutaneous

Reconstitution

Vial size: 10mg

Add BAC water: 1ml

Concentration: 0.1mg per unit

For research and educational use only.

This page provides research dosing information only. Not intended as medical advice. Consult a qualified professional before any use.