Mito Stack: SS-31 (7mg) / MOTS-c (5mg) / NAD+ (500mg)

Longevity / mitochondrial function

Description

The mito stack combines the three most researched mitochondrial-targeted compounds available, each addressing a different failure point in the mitochondrial energy system. ss-31 (elamipretide) repairs the inner mitochondrial membrane by binding and stabilizing cardiolipin — the phospholipid that holds the electron transport chain in place. when cardiolipin degrades with age, electron flow becomes inefficient and reactive oxygen species production spikes. ss-31 fixes this structural problem first. mots-c then acts as the metabolic reprogramming signal — a mitochondria-encoded peptide that activates ampk, driving mitochondrial biogenesis, glucose uptake, and fat oxidation. finally, nad+ supplies the essential coenzyme substrate that every mitochondrial energy process depends on, restoring the declining nad+ pool that drops approximately 50% between ages 40 and 60. the protocol sequence matters: ss-31 first to repair membrane integrity, mots-c added to build new mitochondrial capacity on a repaired foundation, nad+ supporting both throughout. ss-31 received fda accelerated approval as elamipretide/forzinity for barth syndrome in september 2025 — the first mitochondria-targeted therapeutic approved in the us. for research and educational purposes only.

Specifications

Amount in Vial sold as 3-part cycle protocol
BAC Water see individual peptide entries
Amount per Unit see individual entries
Recommended Dose see individual peptide entries for precise dosing
Frequency 12-week protocol — ss-31 weeks 1-3, mots-c weeks 4-8, nad+ throughout
Injection Type Subcutaneous (ss-31, mots-c) / intramuscular (nad+)
Timing Phase 1: SS-31 daily for 21 days to restore membrane integrity. Phase 2: Add MOTS-c every 5 days for 20 days. NAD+: 50-150mg IM, 10 units daily or 2x/week throughout. 2-3 cycles per year.

Dose Calculator

Based on see individual entries (100-unit insulin syringe)

Quick Reference

Category Longevity / mitochondrial function
Dose Range see individual peptide entries for precise dosing
Frequency 12-week protocol — ss-31 weeks 1-3, mots-c weeks 4-8, nad+ throughout
Route Subcutaneous (ss-31, mots-c) / intramuscular (nad+)

Reconstitution

Vial size: sold as 3-part cycle protocol

Add BAC water: see individual peptide entries

Concentration: see individual entries

For research and educational use only.

This page provides research dosing information only. Not intended as medical advice. Consult a qualified professional before any use.

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